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According to the manufacturer, the optimal dosage has not been established, but ethionamide may be used in pediatrics when the organisms are definitely resistant to primary therapy and systemic dissemination of the disease, or other life-threatening complications of tuberculosis, is judged to be imminent.

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WARNING/CAUTIONEven though it may be raresome people may have very bad and sometimes deadly side effects when taking a drugTell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Take this medication by mouth with or without foodusually once daily or as directed by your doctorIf this medication causes stomach upset or nausea/vomitingtake this medication with mealsAlsodiscuss with your doctor if it may be helpful to divide your daily dose into smaller doses to be taken several times a dayFollow your doctor’s instructions carefully.

Which gets me to my pointInstead of focusing all our energy on new drugswhy not improve the drugs we already haveThis is what Alain Baulard and his colleagues at the Pasteur Institute in LilleFrancehave done with the second-line TB drugethionamide.

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